What were some of the major resources of wealth and industry in the original Thirteen Colonies?

Each region of the American colonies had its own form of economic specialization. This was due to the large geographical distances and differences in climate encompassed by the English settlements. For example, the New England colonies, based as they were on the Eastern seaboard, were heavily involved in shipbuilding as well as the manufacture of rum, which could be exported across the Atlantic to the mother country.
The economy of the Southern colonies was, and would remain for centuries, overwhelmingly agrarian. A large variety of crops were grown in the South, most notably cotton, tobacco, indigo, rice, and sugar. The development of these agricultural products—especially cotton—was dependent on slave labor, which formed the basis of Southern economic life right up until the end of the Civil War.
The Middle Colonies, such as Pennsylvania, New York, and Delaware also exported agricultural products, but unlike the Southern colonies, they were able to manufacture iron ore products such as tools, kettles, and plows.