Following Charlie's surgery, he is initially disappointed that he did not become significantly more intelligent overnight. Charlie desperately wishes to improve his intelligence and is upset that the entire process will take some time. Charlie is also upset that Algernon continues to beat him in maze races and desperately wishes to engage in political and religious discussions with the other college students. Dr. Strauss and Professor Nemur eventually give him a TV-like device to listen to as he is sleeping in order to improve his memory, and Charlie gradually becomes more intelligent. Charlie's intelligence eventually improves, and he is finally able to beat Algernon in races and even earns a raise at the bakery for operating the dough-mixer while Oliver is absent. As Charlie's intelligence increases, his co-workers at the bakery begin to resent him, and he struggles to deal with his traumatic memories.
Charlie initially feels a little disappointed after his operation. He was expecting that this potentially ground-breaking new medical procedure would send his IQ into the stratosphere. But nothing seems to have changed, at least not yet. Because fairly soon, Charlie will come to see the benefits of this radical neurological experiment.
Not long after the operation, Charlie starts to experience a sudden, rapid increase in his overall level of intelligence. Before long, he's learned to read, and uses that newfound skill to devour any book that he can lay his hands on. He can also outrun Algernon the mouse, another of the experiment's guinea pigs. This gives him no small sense of satisfaction, not least because he's always been rather jealous of the little mouse.
Unfortunately, Charlie's increased intelligence has made him on an object of suspicion at work. Charlie's coworkers feel threatened by Charlie's sudden increase in brain power and gang up on him, eventually getting him fired from his job at the bakery.
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